4 Little-Known Things That Can Cause Acne Breakouts - You have used all acne treatments that promise clear skin – even avoided food items with a questionable reputation such as chocolate and pizza – and yet, acne continues to show up at the worst of times. Apparently, there are some other things that can contribute to acne breakouts that you probably don’t know. Read on to find out 4 things that might be causing and aggravating your acne.